Friday, April 26, 2013

Measles cases in south Wales outbreak climb to 942

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Measles cases in south Wales outbreak climb to 942
Figure for greater Swansea area rises by 56 as experts warn epidemic shows no sign of easingMeasles cases in south Wales have jumped by 56 in two days as experts warn the outbreak shows no sign of ending.

Source: TheGuardian
Posted on: Thursday, Apr 25, 2013, 11:26am
Views: 15

Source: http://www.labspaces.net/127926/Measles_cases_in_south_Wales_outbreak_climb_to____

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Starting a small business from home - Business Insider

See more Small Business, Big Ideas >>

Daniel Barnett

Daniel Barnett, founder of WORK[etc], says that for him, "sitting behind a desk for 8 hours a day literally brings a cold sweat."

The idea of remote work became controversial recently after Yahoo CEO Marissa Mayer ended the practice there, followed by the end of Best Buy's liberal "results only work environment."

Some managers and companies argue that having people in the office is essential, and that remote workers are harder to monitor and detract from company culture.

But for many small business owners outside of major population centers, remote work is a necessity in one way or another. And many others have family commitments or struggle to function well in an office environment.

For Daniel Barnett, the founder of WORK[etc], a company that's built a business management platform that facilitates remote work, both were true. His entire team of 16 works remotely, from Los Angeles to Essex, England, Australia, Kuala Lumpur, and beyond.

Not only did Barnett feel like he couldn't fully endorse a product he didn't live, his own experience at work inspired him to create it in the first place. "I've waged war with A.D.D. my whole life and the thought of sitting behind a desk for 8 hours a day literally brings a cold sweat," Barnett told us. "Any meeting that goes over 30 minutes is like being locked in a prison cell and the concept of a half-day workshop is pure hell."

He started to develop software tools on his own to free him from having to go to an office for his marketing business, but his A.D.D. led him to go further.

"With A.D.D., starting and finishing routine tasks requires effort and focus. So into the software went simple methods to automate common systems and pull everything together," Barnett said. "For example, (I wanted it to) let me turn a sales lead into a quote, then into a project, and invoice and later a support ticket without having to think about it; manage progress each step of the way so I don't have too."

As the software took care of more and more things, Barnett started to turn it into a business, hoping to help other people work through the things that took so much effort for him.

Of course, there are challenges with running an entirely remote company, even if you're using specialized software. Hiring practices are especially important. You need people that you can trust, that will remain accountable, are comfortable working alone, but are confident enough to jump on a call or Skype to work through ideas or problems.

"Hire someone that thrives off being around people or someone that is shy on a call is going to cause friction," Barnett says.

The company has a very deliberate process to find out of someone's right for the company, and for a remote workplace. "Part of our trial process is for all new employees to set up a WORK[etc] account for an imaginary business, except we don't reveal to that person we are secretly rating their progress," Barnett said. "If they create rubbish names for sales leads, or set up a project with no content then odds are they won't make good remote workers."

And since they're being monitored, it's easy to see if they email their team every simple question rather than having the initiative to at least research the answer themselves, another warning sign.

As someone who constantly experiences and succeeds in a remote work environment, Barnett doesn't buy the arguments against them. "A strategically placed water-cooler, swiss-cheese cubicle walls and bean-bagged chill out rooms do not increase creativity and productivity. Engaged, motivated and inspired people increase productivity and creativity."

In fact, offices can be uniquely unproductive for some people. "I would argue that being politely coerced into small talk about the weather or not being able to avoid [the] latest gossip is a cancer on creativity and productivity," Barnett argues.

The absence of those daily interactions does require a bit of extra effort to keep people engaged, on task, and to build a company culture. To do that, the company asks everyone to spend the last 5 minutes of their day to answer and share their responses to five simple questions:

  1. What did I work on today?
  2. What were the challenges I encountered?
  3. How did I overcome those challenges?
  4. What I am working on tomorrow?

People respond about everything from work to personal lives, in an effort to create a culture where people not only share information, but care for and have concern for the other people on the team.

Beyond the challenges of working remotely, Barnett's trying to break into an incredibly crowded industry, with big enterprise software players like SAP, Salesforce, Oracle, and IBM, along with smaller challengers. "It is frustrating to constantly hear from new customers that they almost didn't sign up because they had never heard of WORK[etc]," Barnett said.

His response? To not worry as much about exposure, keep his head down, and just focus on building a great product. He argues that a major frustration for other small businesses, particularly ones that work remotely, is having to use multiple tools for different things, like sales, project management, invoicing and customer support. "(It's) inefficient and expensive, not to mention downright frustrating," Barnett says.

By offering a single product and a single license, he hopes to provide a cheaper and easier alternative, made by a small business for other small businesses.

Source: http://www.businessinsider.com/starting-a-small-business-from-home-2013-4

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Starting a small business from home - Business Insider

See more Small Business, Big Ideas >>

Daniel Barnett

Daniel Barnett, founder of WORK[etc], says that for him, "sitting behind a desk for 8 hours a day literally brings a cold sweat."

The idea of remote work became controversial recently after Yahoo CEO Marissa Mayer ended the practice there, followed by the end of Best Buy's liberal "results only work environment."

Some managers and companies argue that having people in the office is essential, and that remote workers are harder to monitor and detract from company culture.

But for many small business owners outside of major population centers, remote work is a necessity in one way or another. And many others have family commitments or struggle to function well in an office environment.

For Daniel Barnett, the founder of WORK[etc], a company that's built a business management platform that facilitates remote work, both were true. His entire team of 16 works remotely, from Los Angeles to Essex, England, Australia, Kuala Lumpur, and beyond.

Not only did Barnett feel like he couldn't fully endorse a product he didn't live, his own experience at work inspired him to create it in the first place. "I've waged war with A.D.D. my whole life and the thought of sitting behind a desk for 8 hours a day literally brings a cold sweat," Barnett told us. "Any meeting that goes over 30 minutes is like being locked in a prison cell and the concept of a half-day workshop is pure hell."

He started to develop software tools on his own to free him from having to go to an office for his marketing business, but his A.D.D. led him to go further.

"With A.D.D., starting and finishing routine tasks requires effort and focus. So into the software went simple methods to automate common systems and pull everything together," Barnett said. "For example, (I wanted it to) let me turn a sales lead into a quote, then into a project, and invoice and later a support ticket without having to think about it; manage progress each step of the way so I don't have too."

As the software took care of more and more things, Barnett started to turn it into a business, hoping to help other people work through the things that took so much effort for him.

Of course, there are challenges with running an entirely remote company, even if you're using specialized software. Hiring practices are especially important. You need people that you can trust, that will remain accountable, are comfortable working alone, but are confident enough to jump on a call or Skype to work through ideas or problems.

"Hire someone that thrives off being around people or someone that is shy on a call is going to cause friction," Barnett says.

The company has a very deliberate process to find out of someone's right for the company, and for a remote workplace. "Part of our trial process is for all new employees to set up a WORK[etc] account for an imaginary business, except we don't reveal to that person we are secretly rating their progress," Barnett said. "If they create rubbish names for sales leads, or set up a project with no content then odds are they won't make good remote workers."

And since they're being monitored, it's easy to see if they email their team every simple question rather than having the initiative to at least research the answer themselves, another warning sign.

As someone who constantly experiences and succeeds in a remote work environment, Barnett doesn't buy the arguments against them. "A strategically placed water-cooler, swiss-cheese cubicle walls and bean-bagged chill out rooms do not increase creativity and productivity. Engaged, motivated and inspired people increase productivity and creativity."

In fact, offices can be uniquely unproductive for some people. "I would argue that being politely coerced into small talk about the weather or not being able to avoid [the] latest gossip is a cancer on creativity and productivity," Barnett argues.

The absence of those daily interactions does require a bit of extra effort to keep people engaged, on task, and to build a company culture. To do that, the company asks everyone to spend the last 5 minutes of their day to answer and share their responses to five simple questions:

  1. What did I work on today?
  2. What were the challenges I encountered?
  3. How did I overcome those challenges?
  4. What I am working on tomorrow?

People respond about everything from work to personal lives, in an effort to create a culture where people not only share information, but care for and have concern for the other people on the team.

Beyond the challenges of working remotely, Barnett's trying to break into an incredibly crowded industry, with big enterprise software players like SAP, Salesforce, Oracle, and IBM, along with smaller challengers. "It is frustrating to constantly hear from new customers that they almost didn't sign up because they had never heard of WORK[etc]," Barnett said.

His response? To not worry as much about exposure, keep his head down, and just focus on building a great product. He argues that a major frustration for other small businesses, particularly ones that work remotely, is having to use multiple tools for different things, like sales, project management, invoicing and customer support. "(It's) inefficient and expensive, not to mention downright frustrating," Barnett says.

By offering a single product and a single license, he hopes to provide a cheaper and easier alternative, made by a small business for other small businesses.

Source: http://www.businessinsider.com/starting-a-small-business-from-home-2013-4

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You say you don?t want it, again and again, but you don?t, you don?t really mean it (Unqualified Offerings)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/301608484?client_source=feed&format=rss

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Thursday, April 25, 2013

Rethinking early atmospheric oxygen: Possibility of more dynamic biological oxygen cycle on early Earth than previously supposed

Apr. 24, 2013 ? A research team of biogeochemists at the University of California, Riverside has provided a new view on the relationship between the earliest accumulation of oxygen in the atmosphere, arguably the most important biological event in Earth history, and its relationship to the sulfur cycle.

A general consensus exists that appreciable oxygen first accumulated in Earth's atmosphere around 2.4 to 2.3 billion years ago. Though this paradigm is built upon a wide range of geological and geochemical observations, the famous "smoking gun" for what has come to be known as the "Great Oxidation Event" (GOE) comes from the disappearance of anomalous fractionations in rare sulfur isotopes.

"These isotope fractionations, often referred to as 'mass-independent fractionations,' or 'MIF' signals, require both the destruction of sulfur dioxide by ultraviolet energy from the sun in an atmosphere without ozone and very low atmospheric oxygen levels in order to be transported and deposited in marine sediments," said Christopher T. Reinhard, the lead author of the research paper and a former UC Riverside graduate student. "As a result, their presence in ancient rocks is interpreted to reflect vanishingly low atmospheric oxygen levels continuously for the first ~2 billion years of Earth's history."

However, diverse types of data are emerging that point to the presence of atmospheric oxygen, and, by inference, the early emergence of oxygenic photosynthesis hundreds of millions of years before these MIF signals disappear from the rock record. These observations motivated Reinhard and colleagues to explore the possible conditions under which inherited MIF signatures may have persisted in the rock record long after oxygen accumulated in the atmosphere.

Using a simple quantitative model describing how sulfur and its isotopes cycle through Earth's crust, the researchers discovered that under certain conditions these MIF signatures can persist within the ocean and marine sediments long after O2 increases in the atmosphere. Simply put, the weathering of rocks on the continents can transfer the MIF signal to the oceans and their sediments long after production of this fingerprint has ceased in an oxygenated atmosphere.

"This lag would blur our ability to date the timing of the GOE and would allow for dynamic rising and falling oxygen levels during a protracted transition from an atmosphere without oxygen to one rich in this life-giving gas," Reinhard said.

Study results appear in Nature's advanced online publication on April 24.

Reinhard explained that once MIF signals formed in an oxygen-poor atmosphere are captured in pyrite and other minerals in sedimentary rocks, they are recycled when those rocks are later uplifted as mountain ranges and the pyrite is oxidized.

"Under certain conditions, this will create a sort of 'memory effect' of these MIF signatures, providing a decoupling in time between the burial of MIF in sediments and oxygen accumulation at Earth's surface," he said.

According to the researchers, the key here is burying a distinct MIF signal in deep sea sediments, which are then subducted and removed from Earth's surface.

"This would create a complementary signal in minerals that are weathered and delivered to the oceans, something that we actually see evidence of in the rock record," said Noah Planavsky, the second author of the research paper and a former UC Riverside graduate student now at Caltech. "This signal can then be perpetuated through time without the need to generate it within the atmosphere contemporaneously."

Reinhard, now a postdoctoral fellow at Caltech and soon to be an assistant professor at Georgia Institute of Technology, explained that although the researchers' new model provides a plausible mechanism for reconciling recent conflicting data, this can only occur when certain key conditions are met -- and these conditions are likely to have changed through time during Earth's long early history.

"There is obviously much further work to do, but we hope that our model is one step toward a more integrated view of how Earth's crust, mantle and atmosphere interact in the global sulfur cycle," he said.

Timothy W. Lyons, a professor of biogeochemistry at UCR and the principal investigator of the research project noted that this is a fundamentally new and potentially very important way of looking at the sulfur isotope record and its relationship to biospheric oxygenation.

"The message is that sulfur isotope records, when viewed through the filter of sedimentary recycling, may challenge efforts to precisely date the GOE and its relationship to early life, while opening the door to the wonderful unknowns we should expect and embrace," he said.

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Story Source:

The above story is reprinted from materials provided by University of California - Riverside. The original article was written by Iqbal Pittalwala.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Christopher T. Reinhard, Noah J. Planavsky, Timothy W. Lyons. Long-term sedimentary recycling of rare sulphur isotope anomalies. Nature, 2013; DOI: 10.1038/nature12021

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/YRepc-uxACM/130424185213.htm

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Iran offers to be West's "reliable partner" in Middle East

By Stephanie Nebehay

GENEVA (Reuters) - Iran said on Tuesday it would be a "reliable partner" in the Middle East if Western countries would take a more cooperative approach in talks on its nuclear program.

Western powers blame tension with Iran in part on its refusal to fully cooperate with United Nations calls for curbs on its nuclear activity to ensure it is for peaceful purposes only, and to open up to investigations by U.N. inspectors.

Ali Asghar Soltanieh, Iran's ambassador to the U.N. nuclear watchdog agency, said U.S. and European policies, including extensive sanctions on the Islamic Republic, were bound to fail.

"Western countries are advised to change gear from confrontation to cooperation, the window of opportunity to enter into negotiation for long-term strategic cooperation with Iran, the most reliable, strong and stable partner in the region, is still open," Soltanieh told a meeting in Geneva on the nuclear Non-Proliferation Treaty (NPT).

Soltanieh offered no specifics on how Iran could move to a cooperative dialogue with the West, which has demanded concrete Iranian action to allay international concern that it is trying to develop the means to produce nuclear weapons.

Thomas Countryman, chief U.S. delegate to the NPT talks, said on Monday that Iran's nuclear program poses the greatest threat to the credibility of the NPT, which aims to halt the spread of nuclear weapons.

Soltanieh said Iran was determined to pursue "all legal areas of nuclear technology, including fuel cycle and enrichment technology, exclusively for peaceful purposes" and this would be carried out under International Atomic Energy Agency supervision.

"Hostile policies of Western countries, including dual track, carrot and stick, sanctions-and-talks policies are doomed to failure," he said.

The IAEA said on Tuesday it will hold a meeting with Iran on May 15 aimed at enabling its inspectors to resume a stalled investigation into suspected nuclear bomb research.

Israel suggested on Monday it would be patient before taking any military action against Iran's nuclear program, saying during a visit by U.S. Defense Secretary Chuck Hagel there was still time for other options.

Israel has long hinted at possible military strikes to deny its arch-adversary any means to make a nuclear bomb, while efforts by six world powers to find a negotiated solution with Iran have proved unsuccessful so far.

NUCLEAR-FREE ZONE

Iran and its ally Syria called for a conference aimed at banning nuclear weapons in the Middle East and urged major powers to stop helping Israel to acquire nuclear technology.

The talks, which were supposed to be held last December in Helsinki after being agreed at a 2010 NPT conference, were postponed without a new date being set.

Israel is widely believed to be the Middle East's only nuclear-armed power but neither confirms nor denies having such weapons.

Soltanieh, in an apparent reference to Israel which has not joined the NPT regime, said: "Iran is paying a heavy price for its membership and full commitment to the NPT while others outside the treaty are exempted from any inspection and sanctions, but receiving full nuclear cooperation of western countries, specifically the U.S. and Canada."

Syria's Faysal Khabbaz Hamoui said: "The Israeli nuclear arsenals increase tension in an already explosive situation."

"We call on states, parties, especially nuclear states, to stop their support to Israel in developing its nuclear capabilities and prohibit providing it with nuclear technology. This should help pave the way for a zone free of weapons of mass destruction and nuclear weapons in the Middle East," he said.

(Reporting by Stephanie Nebehay; Editing by Jon Hemming)

Source: http://news.yahoo.com/iran-offers-wests-reliable-partner-mideast-131919179.html

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